A 17-year-old teenage girl presents with menorrhagia and a family history of heavy periods and hysterectomy, suggestive of Von Willebrand Disease (VWD). Which statement about VWD is correct?
A. There are multiple VWD patterns; most are autosomal dominant (AD).
B. Treatment involves iron supplementation only.
C. It affects females more than males, with a ratio of approximately 2:1.
D. It is an X-linked recessive disorder.
E. Type 1 is the most severe form.
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